Last Updated: January 2026

Plasma Donation Requirements 2026

Everything you need to know about plasma donation eligibility. Check if you qualify and learn how to pass your first screening.

Complete Eligibility Checklist 2026 Requirements

Quick Eligibility Checklist

Before visiting a plasma center, make sure you meet these basic requirements:

Age 18-69 (some centers accept 18-74)
Weight at least 110 lbs (50 kg)
Generally good health
Valid government-issued ID
Proof of address (utility bill, bank statement)
Social Security card or proof of SSN
No recent illness or infection
Pass health screening tests

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Detailed Eligibility Requirements

Age Requirements

You must be at least 18 years old to donate plasma. Most centers accept donors up to age 69, though some (like CSL Plasma) accept donors up to age 74. First-time donors over 65 may need additional health clearance.

Weight Requirements

Weight Range Plasma Volume Typical Payment
110-149 lbs 690 mL $30-50
150-174 lbs 750 mL $40-55
175+ lbs 880 mL $50-65

Tip: Heavier donors can donate more plasma per session, often resulting in higher compensation.

Health Screening Tests

Every visit includes these quick tests:

Vital Signs

  • • Blood pressure (max 180/100)
  • • Pulse (50-100 bpm)
  • • Temperature (under 99.5°F)

Blood Tests

  • • Protein levels (min 6.0 g/dL)
  • • Hematocrit (38-54%)
  • • First visit: HIV, Hepatitis screening

What Disqualifies You From Donating Plasma?

Permanent Disqualifications

  • x HIV positive or AIDS diagnosis
  • x Hepatitis B or C (ever had)
  • x IV drug use (even once)
  • x Ebola virus survivors
  • x Blood transfusion in the UK (1980-1996)
  • x Hemophilia or bleeding disorders

Temporary Deferrals

Condition Waiting Period
Cold or flu Until symptom-free
Tattoo or piercing (licensed shop) 3-4 months
Tattoo (unlicensed) 12 months
Pregnancy 6 weeks postpartum
Antibiotics Until course complete + 24-48 hours
Surgery 6 months (major) / 2 weeks (minor)
Travel to malaria-risk areas 12 months
COVID-19 positive 14 days after symptom-free

Medications That May Affect Eligibility

Important: Always bring a list of your current medications to your screening. Many common medications are fine, but some require deferrals.

Usually OK:

  • • Birth control pills
  • • Blood pressure medications
  • • Antidepressants (most)
  • • Allergy medications
  • • Thyroid medications

May Disqualify:

  • • Accutane (isotretinoin) - 1 month wait
  • • Blood thinners (warfarin, etc.)
  • • Insulin
  • • HIV medications (PrEP ok at some centers)
  • • Experimental medications

How to Pass Your First Screening

Before Your Visit

  • 1. Drink plenty of water (64+ oz) starting the day before
  • 2. Eat a protein-rich meal 2-3 hours before
  • 3. Avoid fatty foods, caffeine, and alcohol
  • 4. Get a good night's sleep
  • 5. Gather all required documents

Documents to Bring

  • • Valid government ID (driver's license, state ID, passport)
  • • Social Security card OR document showing full SSN
  • • Proof of current address (utility bill, bank statement, lease - dated within 30-60 days)

Pro Tip: First visits take 2-3 hours due to the physical exam and health history. Subsequent visits are 45-90 minutes. Bring headphones and entertainment!

GM

Written by

Glen Meade

Side hustle expert who has personally tested 50+ platforms since 2019. Sharing real earnings data and honest assessments to help you find legitimate income opportunities.

Last updated: January 2026